Friday, 14 November 2008

Changes in Physical Function After Palliative Surgery for Metastatic Spinal Tumor

Link to journal
Yamashita, Takayuki ; Aota, Yoichi ; Kushida, Kazuyoshi ; Murayama, Hitoshi et al
Changes in Physical Function After Palliative Surgery for Metastatic Spinal Tumor: Association of the Revised Tokuhashi Score With Neurologic Recovery
Spine. 33(21):2341-2346, October 1, 2008.
Study Design. A retrospective study of patients undergoing palliative surgery for metastatic spinal tumors.Objective. To investigate short-term functional recovery and duration of improvement after palliative surgery, to correlate these outcomes with the revised Tokuhashi score, and to examine the relationship between function and neurologic deterioration.Summary of Background Data. The revised Tokuhashi score is a scoring system used to predict life expectancy for patients with metastatic spinal tumors. The relationship between the revised Tokuhashi score and physical functional improvement after palliative surgery has not been examined previously.Methods. The clinical charts of 86 patients were reviewed. The Eastern Cooperative Oncology Group Performance Status (ECOG-PS) was used to assess physical function. Each score was documented before surgery and at every month after surgery. The duration of ECOG-PS improvement, defined as the period between surgery and deterioration to the preoperative ECOG-PS grade, was correlated with the revised Tokuhashi score.Results. The ECOG-PS grade improved in 44 (51.1%) patients at 1 month postoperative. When ECOG-PS improvement was found after surgery, it persisted above the preoperative level for an average of 9.3 months. At 1 month postoperative, patients scoring 0 to 8 on the total revised Tokuhashi score had significantly lower ECOG-PS improvement (26 of 55 patients) when compared to patients with higher scores (18 of 27 patients, P <>

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